Looking for a bold and flavorful dinner idea that combines creamy pasta with juicy chicken? This Garlic Butter Chicken Bites with Spicy Cajun Alfredo Twisted Pasta recipe is the perfect comfort food with a kick! It’s rich, cheesy, and loaded with Cajun spice — making it a must-try for pasta and chicken lovers.
Why You’ll Love This Cajun Chicken Pasta Recipe
This creamy Cajun Alfredo pasta is the ultimate fusion of savory garlic butter chicken bites and spicy Alfredo sauce tossed with perfectly cooked twisted pasta like rotini or fusilli. Whether you’re cooking for family dinner or impressing guests, this easy one-pan recipe delivers restaurant-quality flavor in just 35 minutes.
🧄 Ingredients You’ll Need
For the Garlic Butter Chicken Bites:
1.5 lbs boneless, skinless chicken breast, cut into bite-sized pieces
3 tbsp butter
4 garlic cloves, minced
1 tsp smoked paprika
1 tsp Cajun seasoning
Salt and black pepper, to taste
For the Spicy Cajun Alfredo Pasta:
12 oz twisted pasta (fusilli or rotini)
2 tbsp butter
3 garlic cloves, minced
1.5 cups heavy cream
1 cup grated Parmesan cheese
½ cup shredded mozzarella cheese
1 tsp Cajun seasoning (adjust to taste)
½ tsp crushed red pepper flakes (optional, for extra heat)
Salt and black pepper, to taste
Fresh parsley, chopped (for garnish)
👩🍳 How to Make Garlic Butter Chicken Bites with Cajun Alfredo Pasta
Step 1: Cook the Pasta
Bring a large pot of salted water to a boil. Add the twisted pasta and cook until al dente according to the package instructions. Drain and set aside.
Step 2: Sauté the Chicken
In a large skillet, melt 3 tablespoons of butter over medium-high heat. Add the minced garlic and sauté for 30 seconds until fragrant. Toss in the chicken pieces, smoked paprika, Cajun seasoning, salt, and pepper. Cook for 6–8 minutes, or until golden brown and cooked through. Remove the chicken and set it aside.
Step 3: Make the Cajun Alfredo Sauce
Using the same skillet, melt 2 tablespoons of butter over medium heat. Add the minced garlic and sauté for about 1 minute. Slowly pour in the heavy cream while stirring constantly. Bring to a simmer and whisk in the Parmesan and mozzarella cheese until the sauce becomes thick and creamy. Stir in Cajun seasoning and red pepper flakes to taste. Season with salt and black pepper.
Step 4: Combine Pasta and Sauce
Add the cooked twisted pasta to the skillet and toss to coat it evenly with the spicy Alfredo sauce.
Step 5: Add Chicken and Serve
Return the chicken bites to the skillet. Stir gently to combine and allow everything to heat together for about 2 minutes. Garnish with fresh chopped parsley and serve hot.
⏱ Recipe Summary
Prep time: 10 minutes
Cook time: 25 minutes
Total time: 35 minutes
Servings: 4
Calories: ~850 kcal per serving
🌟 Tips for the Best Spicy Cajun Pasta
Use fresh garlic for maximum flavor.
Adjust the Cajun seasoning and red pepper flakes based on your heat preference.
For extra protein, you can add shrimp or andouille sausage alongside the chicken.
Perfect For Meal Prep or Family Dinners
This creamy garlic butter chicken pasta stores well and makes great leftovers. Just reheat gently with a splash of cream or milk to revive the sauce. It’s ideal for busy weeknights, date night at home, or when you’re craving something indulgent and spicy.
Try this garlic butter Cajun chicken pasta recipe today and bring bold flavors to your dinner table!